htmldocs comes with Tailwind CSS v3.4.3 bundled by default. The @tailwindcss/typography plugin (v0.5.9) is included by default. The default examples use Tailwind classes.

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Customizing Tailwind

Your project includes a tailwind.config.js file that you can customize. The default configuration is optimized for document generation: 
module.exports = {
  content: ["./documents/**/*.{js,jsx,ts,tsx}"],
  theme: {
    extend: {
      fontFamily: {
        serif: ['Palatino', 'Palatino Linotype', 'serif'],
      },
      typography: {
        DEFAULT: {
          css: {
            fontSize: '12pt',
            lineHeight: 1.5,
            color: '#000000',
          }
        }
      }
    }
  },
  plugins: [
    require('@tailwindcss/typography'),
  ],
};

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Usage

Use Tailwind classes in your document templates. 
import { Document, Page } from 'htmldocs';

export default function Resume() {
  return (
    <Document>
      <Page className="bg-white p-8">
        <div className="prose">
          <h1>John Doe</h1>
          <p>Professional software engineer</p>
        </div>
      </Page>
    </Document>
  );
}
The prose class from @tailwindcss/typography is recommended for content-heavy sections.